Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gli1  GLI-Kruppel family member GLI1   (Synonyms: Zfp5, Zfp-5)
Results	Reference
1*	J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
1	J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217
1	J:314666 Balasubramanian R, Min X, Quinn PMJ, Giudice QL, Tao C, Polanco K, Makrides N, Peregrin J, Bouaziz M, Mao Y, Wang Q, da Costa BL, Buenaventura D, Wang F, Ma L, Tsang SH, Fabre PJ, Zhang X, Phase transition specified by a binary code patterns the vertebrate eye cup. Sci Adv. 2021 Nov 12;7(46):eabj9846
1*	J:59288 Baur ST, Mai JJ, Dymecki SM, Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development. 2000 Feb;127(3):605-19
1	J:339096 Biswas S, Chan CS, Rubenstein JLR, Gan L, The transcription regulator Lmo3 is required for the development of medial ganglionic eminence derived neurons in the external globus pallidus. Dev Biol. 2023 Aug 1;503:10-24
1	J:266003 Caballero IM, Manuel MN, Molinek M, Quintana-Urzainqui I, Mi D, Shimogori T, Price DJ, Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer. Cell Rep. 2014 Sep 11;8(5):1405-18
1	J:198655 Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X, Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development. 2013 Jul;140(13):2711-23
1*	J:150375 Cobourne MT, Xavier GM, Depew M, Hagan L, Sealby J, Webster Z, Sharpe PT, Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49
1	J:171198 Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA, Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina. J Neurosci. 2011 Mar 30;31(13):5169-80
1	J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73
1	J:257526 Feuerstein M, Chleilat E, Khakipoor S, Michailidis K, Ophoven C, Roussa E, Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line. Cell Tissue Res. 2017 Nov;370(2):211-225
1	J:147878 Gao B, Hu J, Stricker S, Cheung M, Ma G, Law KF, Witte F, Briscoe J, Mundlos S, He L, Cheah KS, Chan D, A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature. 2009 Apr 30;458(7242):1196-200
1*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1	J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192
1*	J:155096 Han J, Mayo J, Xu X, Li J, Bringas P Jr, Maas RL, Rubenstein JL, Chai Y, Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice. Development. 2009 Dec;136(24):4225-33
1	J:189675 Haraguchi R, Matsumaru D, Nakagata N, Miyagawa S, Suzuki K, Kitazawa S, Yamada G, The hedgehog signal induced modulation of bone morphogenetic protein signaling: an essential signaling relay for urinary tract morphogenesis. PLoS One. 2012;7(7):e42245
1*	J:119913 Haraguchi R, Motoyama J, Sasaki H, Satoh Y, Miyagawa S, Nakagata N, Moon A, Yamada G, Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling. Development. 2007 Feb;134(3):525-33
1*	J:49252 Hardcastle Z, Mo R, Hui CC, Sharpe PT, The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development. 1998 Aug;125(15):2803-11
1	J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43
1	J:160733 Ivaniutsin U, Chen Y, Mason JO, Price DJ, Pratt T, Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex. Neural Dev. 2009;4:3
1	J:172044 Katayama K, Melendez J, Baumann JM, Leslie JR, Chauhan BK, Nemkul N, Lang RA, Kuan CY, Zheng Y, Yoshida Y, Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7607-12
1	J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126
1	J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90
1	J:245974 Li J, Cui Y, Xu J, Wang Q, Yang X, Li Y, Zhang X, Qiu M, Zhang Z, Zhang Z, Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development. J Biol Chem. 2017 Sep 22;292(38):15814-15825
1	J:332136 Li X, Gordon PJ, Gaynes JA, Fuller AW, Ringuette R, Santiago CP, Wallace V, Blackshaw S, Li P, Levine EM, Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis. Elife. 2022 Dec 2;11
1	J:275488 Lim Y, Cho IT, Shi X, Grinspan JB, Cho G, Golden JA, Arx Expression Suppresses Ventralization of the Developing Dorsal Forebrain. Sci Rep. 2019 Jan 18;9(1):226
1*	J:335090 McLaughlin MT, Sun MR, Beames TG, Steward AC, Theisen JWM, Chung HM, Everson JL, Moskowitz IP, Sheets MD, Lipinski RJ, Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis. Dev Dyn. 2023 Apr;252(4):483-494
1	J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82
1*	J:206883 Murashima A, Akita H, Okazawa M, Kishigami S, Nakagata N, Nishinakamura R, Yamada G, Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm. Dev Biol. 2014 Feb 1;386(1):216-26
1	J:97323 Niedermaier M, Schwabe GC, Fees S, Helmrich A, Brieske N, Seemann P, Hecht J, Seitz V, Stricker S, Leschik G, Schrock E, Selby PB, Mundlos S, An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression. J Clin Invest. 2005 Apr 1;115(4):900-909
1*	J:39659 Platt KA, Michaud J, Joyner AL, Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice. Mech Dev. 1997 Mar;62(2):121-35
1	J:335153 Qiu T, Huteckova B, Seppala M, Cobourne MT, Chen Z, Hovorakova M, Buchtova M, Tucker AS, Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling. Development. 2023 Apr 1;150(7):dev201464
1	J:264120 Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND, Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFbeta signaling. Development. 2018 Jul 9;145(13):dev159947
1*	J:88955 Schwabe GC, Trepczik B, Suring K, Brieske N, Tucker AS, Sharpe PT, Minami Y, Mundlos S, Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn. 2004 Feb;229(2):400-10
1*	J:92054 Taglialatela P, Soria JM, Caironi V, Moiana A, Bertuzzi S, Compromised generation of GABAergic interneurons in the brains of Vax1-/- mice. Development. 2004 Sep;131(17):4239-49
1	J:204446 Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R, Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:309718 Veistinen LK, Mustonen T, Hasan MR, Takatalo M, Kobayashi Y, Kesper DA, Vortkamp A, Rice DP, Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets. Front Physiol. 2017;8:1036
1	J:103124 Wang Y, Dakubo GD, Thurig S, Mazerolle CJ, Wallace VA, Retinal ganglion cell-derived sonic hedgehog locally controls proliferation and the timing of RGC development in the embryonic mouse retina. Development. 2005 Nov;132(22):5103-13
1	J:182757 Wilson DG, Phamluong K, Lin WY, Barck K, Carano RA, Diehl L, Peterson AS, Martin F, Solloway MJ, Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25
1	J:321577 Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Gunther A, Stainier DYR, Samakovlis C, An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea. Development. 2022 Feb 1;149(3):dev199804
1	J:97242 Zhang XQ, Afink GB, Hu XR, Nister M, Forsberg-Nilsson K, Gli1 is not required for Pdgfralpha expression during mouse embryonic development. Differentiation. 2005 Mar;73(2-3):109-19
1*	J:54600 Zhang Y, Zhao X, Hu Y, St. Amand T, Zhang M, Ramamurthy R, Qiu M, Chen Y, Msx1 is required for the induction of Patched by Sonic hedgehog in the mammalian tooth germ. Dev Dyn. 1999 May;215(1):45-53
1*	J:70832 Zulch A, Becker MB, Gruss P, Expression pattern of Irx1 and Irx2 during mouse digit development. Mech Dev. 2001 Aug;106(1-2):159-62